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Does the high prevalence of mosaicism in our tissues mean that it is impossible to recognize and eliminate cells with subtle mutations and that suboptimal cells are bound to accumulate within organs?
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Prostitutes often wear all-concealing chadors, making it impossible to recognize them, and even the logistics of the business are shadowy.
Conversely, the very notion of "normal" and "healthy" would not exist if it were impossible to recognize a qualitative (and not merely a graded) distinction between affected and unaffected tissues.
Without these compentencies, it is impossible to recognize the potential and the result of evolutionary processes in biological diversity (new species and adaptations, new vital strategies).
This phenotype was previously impossible to recognize in fixed preparations and masked by the overall increase in mistargeting penetrance.
"No man's land," the deadly strip between the walls that separated east and west, is all but impossible to recognize -- buried under shopping centers, office buildings and new apartments.
It is impossible to recognize all the possible regulatory elements, and absolutely confident results on mutation rates are hard to obtain.
It is impossible to recognize objects that are too close together, and the critical spacing for recognition grows proportionally with eccentricity (Bouma, 1970; Levi, 2008; Pelli & Tillman, 2008).
We classified intervascular transparency into three categories: (i) preserved; (ii) slightly impaired (not completely transparent, but easily recognizable subepithelial vessels); and (iii) impaired (difficult or impossible to recognize subepithelial vessels).
In some cases they are very schematically formed, and it is often difficult or impossible to recognize female attributes.
In the absence of subsidence indications including well protrusion and casing failures, it is almost impossible to recognize occurrence of subsidence in absence of periodic ground-surface level measurements are conducted using surveying, extensometers, InSAR methods, etc. [11].
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