He added, with a nod to a fellow filmmaker: "It is not impossible to make mainstream films which are really good.
But, until the recent clinical trials, it was impossible to convince mainstream experts that the lower rates were not because of other factors, like polygamy or harsh penalties for extramarital sex under Shariah, the legal code of Islam based on the Koran.
AllMusic commented on Dr. Dre's efforts, "Here, Dre established his patented G-funk sound: fat, blunted Parliament-Funkadelic beats, soulful backing vocals, and live instruments in the rolling basslines and whiny synths" and that "For the next four years, it was virtually impossible to hear mainstream hip-hop that wasn't affected in some way by Dre and his patented G-funk".
It was impossible to avoid the mainstream conversation.
Coupled with the fact that cannabis is now fully legal in 10 states, it's impossible to ignore the mainstream acceptance of what was once an illicit herb.
Even beyond that, unconventional casting creates a special bond between the character and the audience, because celebrity culture renders it nearly impossible to engage with mainstream art without assigning value to the faces we watch onscreen.
But if there is a renaissance among the female cast members, there's also a sense of something missing, a quality that may simply be impossible to wedge into a mainstream institution like "Saturday Night Live" -- a show that began as the vanguard of humor, but lost that role long ago.
Even if you have large sums of cash at your disposal – and most people don't – it is pretty much impossible to find an alternative mainstream educational environment for a child who doesn't thrive at a conventional school, even if this is for a good reason.
But these days it has become impossible to tell where the mainstream stops and the fanatical fringe begins.
It looks like Hillary Clinton's nomination as the Democratic candidate is assured, but are Bernie Sanders' economic proposals impossible to achieve, as many mainstream economists maintain?
