He confirmed what others in his focus group noted about the challenges of using Guidelines and the impossibility of trying to include every item, saying "I whined to my advisor [when I was a fellow] about that very problem—[the document you create if you use SQUIRE exactly as written is unintelligible].
This article has been updated to include the definition of meteor and to note the impossibility of a meteor striking Earth.
Limitations of the GCS include the impossibility to assess the verbal score in intubated or aphasic patients, and an inconsistent inter-rater reliability.
For 15 experimentally tested carbon sources (out of 20 carbon sources tested in silico) we obtain 100% agreement between the predicted utilization of alternative carbon sources by C. difficile, including the impossibility to use lactose as a carbon source.
We should also consider that the EAT is a screening, self-report instrument, with all the limitations that this entails, including the impossibility to exclude dissimulative behavior and hiding the symptoms on behalf of patients.
Exclusion criteria included heavy handicap with impossibility to come to the hospital, language limitations (not speaking Arabic), and lack of informed consent.
The majority could not be included because of visible inflammatory changes (61) or impossibility to reach the terminal ileum (16).
Our first approach focused on diosmetin determination after enzymatic degradation, and these issues have been reflected in the impossibility to find a totally free blank matrix even if the volunteers included in this study have kept a strict diet.
This had been delayed by Italian and German demands that air transport be included, which was perhaps a delaying tactic given the impossibility to doing so effectively.
Most of the inoculated mice (85/90 in group 1a and 37/41 in group 1b) developed clinical symptoms, including hunched posture, weight loss, reduced mobility, tail chewing, clasping and difficulty or impossibility to stand up.
