Recent data of Buckler at al in mice suggest that by negatively regulating TCR-mediated signals, PTEN imposes a requirement for CD28 co-stimulation to assure T-cell proliferation and survival [45].
The first residues (REKKK) of this loop in TOR form a cluster of charged residues that imposes a requirement for surface exposure.
To reduce this problem of potential DNA lesions at off-target sites, two promising practical solutions have been developed to impose a requirement for two gRNA target recognition sites.
With the long discharge duration of about 1000 s, that imposes a requirement of sampling data for an equally long duration from the variety of fast and slow diagnostics, the challenge is also to cater the need of a real time monitoring of signals by multiple locally networked users.
In Minnesota, the main momentum in the shift toward wind has come from the Legislature, which in 1994 imposed a requirement calling for Northern States Power, Xcel's predecessor, to have 425 megawatts of wind power capacity in service or under contract by the end of 2002.
A regulation, for example, that imposed a requirement on all restaurants "operating 10 or more restaurants under the same name," would not be pre-empted, he wrote.
Imposing a requirement of national service — for men and women and without college deferments — would be doing our nation and the world a huge favor.
The technical regulation restricts international trade by imposing an authorisation requirement for SVHC listed in Annex XIV REACH and that are used in imported articles.
For example, 20% of doctors and 65% of nurses impose a parity requirement for use of pills, a common spacing method that is medically acceptable to use at any parity.
Those measures, which will appear on the ballot on March 2, would impose a constitutional requirement for a balanced budget and allow the state to borrow up to $15 billion to help pay for past deficits.
