Sentence examples for imposes deleterious from inspiring English sources

Lynch and Richardson [ 15] argued that harbouring introns imposes deleterious effects because errors in splicing can lead to a failure in producing functional proteins.

Physical activity, known to provide a number of benefits for noninfected individuals, can exert positive effects on metabolic and cardiovascular functions while not imposing deleterious effects on the immune system.

The loss of members from a family in some clades/species can be due to the loss of the physiological constraints that previously impose as deleterious the absence of this family [ 50].

These workers showed that insertions or deletions within the N-terminal tail do not impose any deleterious growth phenotype at all tested temperatures, as long as a 33-residue essential END domain, that interacts with the Ctf19-Mcm21-Okp1 kinetochore sub-complex, is preserved.

Comparison to existing estimates in humans suggests that a substantial fraction of the total burden imposed by recessive deleterious variants is due to single mutations that lead to sterility or death between birth and reproductive age.

Economists describe a situation in which the decision to use a commodity that produces a deleterious byproduct that imposes costs on other persons, who are not part of the decision, as a negative externality.

If the primary goal of cancer research is to reduce the deleterious effects cancer imposes on society and victims, two issues must be addressed to enact a cancer research policy that best achieves this goal.

If the stress is imposed from within by deleterious mutations it implies the existence of negative (synergistic) epistasis.

This homosynaptic homeostatic regulation is expected to play an important role in preventing the deleterious situations imposed by Hebbian plasticity to secure long-term synaptic stability.

These examples suggest that plethodontids have evolved features that offset deleterious effects imposed by their expanding genomes (Wiggers and Roth 1991; Roth et al. 1997), indicating that an unusual balance between TE proliferation, host silencing, and selection on organism-level traits underlies the huge genome sizes in salamanders.

A previous study [ 18] has shown that in a spatial replicator system with complex formation, a deleterious mutation that destroys both catalytic and template activity of replicators imposes a great disadvantage to parasitic replicators because of the effective dilution of the system by inert molecules.