Integration of a centromere close to ARS1 N in this plasmid (pΔ9C) resulted in a marked bias toward ARS1 N use, indicating that sequences that are known to advance origin activation time in chromosomal DNA can in fact impose an origin use bias in pN&S.
Initiated by the disturbance, Equation (2), imposed around the origin in the finite extent, |y|
This dialogue serves as the locus classicus for the notion of an externally-imposed origin of living beings through the action of an intelligent Craftsman (demiurgos) who created the cosmos and all living beings in accord with eternal archetypes or forms, realizing through this both aesthetic and rational ends.
Callaghan et al.'s approach was driven by constraints imposed by the same origin policy.
These results suggest that during DNA replication under stressful conditions, ATR-mediated phosphorylation of Mcm2 promotes chromatin recruitment of Plx1, which subsequently releases the block on origin firing imposed by the intra-S-phase checkpoint.
In common with many other polyploids, it seems that a severe genetic bottle-neck was imposed at the species origin, via hybridisation of two wild species and spontaneous chromosome duplication.
The singularity of cylindrical or spherical coordinate systems at the origin imposes certain regularity conditions on the spectral expansion of any infinitely differentiable function.
The physiological relevance of vitamin E and the severe pathological consequences of its deficiency, such as neurological disorders or lung diseases, together with its dietary origin impose a major challenge for sustaining an adequate supply of this vitamin to different tissues [31].
Lysosomal substrates of extracellular origin impose a particular load on macrophages and other phagocytic myeloid cells that process microbes, senescent cells and effete tissue material [ 11, 30].
The distinction between asteroids and meteoroids having the same origin is culturally imposed and is basically one of size.
We imposed no limitation by regional origin, study design, or nature of the control group, which could consist of day workers or the general population.
