The company also tried to argue that the case was not important enough to warrant direct review, even though in a previous brief Microsoft said the remedy imposed on the company "could have a significant adverse impact on the nation's economy".
The second world war inflicted not only physical damage on the City of London but also imposed a significant human cost on the financial sector in terms of international connections and loss of knowledge.
The results revealed that the treatment temperature and duration imposed a significant effect on the surface color and contact angle of the bamboo.
Addition of starch in the production medium imposed a significant effect on siderophoregenesis by A. faecalis whilst, siderophore production by P. aeruginosa strain EGYII DSM 101801 did influence negatively by starch addition in the production medium.
Buttressed by related studies on smaller natural proteins with chain lengths of ∼40 residues, our findings argue that the de novo native topology of Top7 likely imposed a significant restriction on the cooperativity achievable by any design for this target structure.
By 2013 the 250 wolves in the Western Alps imposed a significant burden on traditional sheep and goat husbandry with a loss of over 5,000 animals in 2012.
Recently an analysis of the cost effectiveness of trastuzumab has been conducted as this agent has imposed a significant burden on healthcare budgets worldwide (Norum et al. 2005).
In contrast, in the subsets of '<5 hours', '<6 hours', '<7 hours'<8 '<8 hours'<9 '<9 hours' , and '<10 hours' , each additional hour of waiting in each subset imposed a significant difference on the probability of death.
Most other countries where large multinational companies have their headquarters have territorial systems that do not impose domestic taxes on a significant share of the foreign earnings of these companies.
So the voter ID laws make exercise of important rights contingent upon showing a state ID without any serious rationale and, furthermore, impose unnecessary burden on a significant number of voters.
