> -wrap-foot> Experts were asked to use the method of their choice; no further requirements were imposed regarding methodology.
Thus, we have ∼16 19% of the variation unaccounted for, but given that there is a small measurement error in the determination of A1C (perhaps 2 5%), and a larger coefficient of variation in the measurement of glucose (10 20%), the constraints imposed by methodology can explain the residual variation.
Moreover, I fully support the suggestion that 'further research is warranted to examine more closely the potential active role of researcher-imposed methodologies in encouraging overestimation of young people's alcohol related perceptions' ([ 61], p. 1083).
Two main assumptions are imposed in our methodology: first, the subunits do not undergo significant conformational changes in forming different complexes, and second the arrangements of subunits in the different oligomers are consistent between sub-complexes.
Additionally, limitations imposed on the methodology due to the pragmatic considerations mentioned earlier often mean that while the research results obtained are not wrong, they may not be proven to an academic standard, constraining the ability to publish.
Thus, all three methods have its limitations, and although the importance of HGT is clear, the numbers obtained may be subject to certain bias imposed by the methodology [ 41].
Measuring brain activity while the infant takes part in a still face paradigm is still not possible as because of the constraints imposed by MRI methodology – one needs to lie very still which can only happen if infants are asleep.
In developing this new methodology, we imposed several requirements: As in state-space models, we use estimates of spatial accuracy as a source of information to infer a probable animal position for a given time.
Also, the response rate could not be calculated since, due to practical limitations imposed by the survey methodology, the number of clinicians invited to participate in the survey that met the relatively stringent inclusion criteria was not possible to determine.
An example from evolutionary electronics illustrates some of the constraints imposed by the rational design methodology itself.
The approach relies on the analysis of a single unit cell, making use of Bloch theorem along with the application of a harmonic balance methodology over an imposed solution ansatz.
