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Importantly, normal Purkinje cell positioning is not required for restricted zebrin II expression as it is expressed in parasagittal subsets of ectopic Purkinje cells in several dispersal mutants (e.g., disabled-19; weaver–40; cerebellar deficient folia-41).
Importantly, normal SVZ cells responded in a different way; indeed, by chemically stabilizing HIF-1α, REDD1 was transiently upregulated and Akt/mTOR pathway was not inhibited, unlike in tumor cells, following exposure to high oxygen tension (Figure 3H), and Akt and Stat3 were eventually upregulated by CoCl2.
Importantly, normal skeletal muscle growth was not impaired in AT1a−/− mice as no differences were observed in myofibre CSA between uninjured WT and AT1a−/− mice (Figure S7), however our data suggests that post-natal induced muscle growth following injury requires Ang II.
Importantly, normal colon epithelial cells were not affected by the combination.
Importantly, normal frataxin levels appear to be required for optimal p53 activation following hypoxia.
Importantly, normal tissue histology was observed for intestine, tumor, and liver by H&E staining.
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Importantly, normal-length Cw6-GFP and Cw6-mCherry co-localised at the IS, confirming that the type of the fluorescent tag itself did not affect segregation (Pearson coefficient r = 0.77±0.14, n = 6; Figure 5).
Importantly, in normal breast tissue slices infected with AdCXCR4, no luciferase protein expression could be visualized, whereas in normal breast tissue infected with AdCMV luciferase protein, expression was seen.
Most importantly, the normal optical states can be regulated from opaque to transparent through microstructure control, showing great potential E-O applications in practical uses.
Importantly, a normal MRI imaging does not rule out the diagnosis of OD as the aforementioned findings lag behind the clinical onset of the disease [118, 122, 123].
Importantly, while normal leaf tissue shows a typical split signal with both a negative and a positive peak in the induced fractional circular polarization and circular dichroism, the signals close to the veins only display a negative band.
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