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The cells were differentiated into the hepatic lineage resulting in hepatocyte-like cells that showed some features of mature hepatocytes and, most importantly, exhibited molecular characteristics of the diseased phenotypes (α1-antitrypsin deficiency, familial hypercholesterolaemia and glycogen storage disease type 1α, respectively).
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MiR-101 is frequently silenced in human cancers and, importantly, exhibits antitumorigenic properties when overexpressed.
Not only were lactation-associated adipocytes significantly smaller in size (P = 0.01) but, more importantly, they exhibited features consistent with lipolysis [ 40] including prominent membrane folding and vesicle formation.
More importantly, it exhibited preferential adsorption of C2H6 over C2H4.
Importantly, 10a exhibited more than 8300 fold selectivity for MMP-2 versus MMP-9 (IC50 = 1.58 μM).
Importantly, they exhibited favorable biocompatibility with excellent performance in longitudinal relaxivity rate (r1) of 6.45 mM−1S−1 and radiosensitization enhancements.
Most importantly, hybrids exhibited superior methanol tolerance, remaining stable after the addition of 2 M methanol in electrolyte.
More importantly, 2CzPy exhibited a low efficiency roll-off at a brightness of 1000 cd m−2 with an external quantum efficiency of 17.1% (3.9% roll-off).
Importantly, they exhibited a vast reduction in the number of input parameters, this being valuable for end-to-end network training, where a substantial number of low-level features with small input receptive fields are incorporated.
Importantly, TPL exhibited a far greater antitumor effect on ErbB2-overexpressing gastric cancer cell line than trastuzumab plus pertuzumab, suggesting that it may be a promising agent for the treatment of gastric cancer.
Importantly, they exhibited restricted diffusion inside but Brownian diffusion outside presynaptic terminals.
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