Traumatic brain injury (TBI), including mild TBI (mTBI), is importantly associated with vigilance and sleep complaints.
Acetylcholinesterase inhibitors, dopamine agonists, and selective serotonin reuptake inhibitors were the drug classes most importantly associated with sleep disturbance.
Nonetheless, long-term survival in this population has been more importantly associated with pre-morbid illnesses and functional ability at hospital discharge than with acute illness factors [14, 15].
These practices should be strongly discouraged, as they are importantly associated with diarrhoea morbidity and mortality.
This study shows that medical comorbidities are importantly associated with direct (obstetric) deaths.
Our results do not provide strong evidence that facial morphology is robustly and importantly associated with cardiometabolic risk factors.
Importantly, Nestin expression was significantly associated with poor survival in patients with triple-negative breast cancer.
Consistent with our proteomics result, lb2 mRNA localizes to axons and GCs in culture and, importantly, associates with translating ribosomes in retinal axons in vivo.
Importantly, genes associated with macrophage function such as the toll-like receptors (TLR) 1 and 4, CD14, or components of the NF-κB signaling pathway (gene ontology activation of innate immune response (GO: 0002218)) were significantly upregulated in iPSC-Mac and PBMC-Mac versus iPSC, whereas the opposite could be observed when analyzing genes associated with pluripotency (Fig. 2d).
Importantly, genes associated with cancer progression (i.e., Itgb2, Itgb5, paxillin, fyn) displayed increased expression, whereas those thought to suppress progression (i.e., vinculin, gravin) exhibited decreased levels of expression compared to MOSE-E cells.
Importantly, HIF1α associated with the genomic region containing this HRE motif upon exposure of c2c12 cells to hypoxia (Figure 3B), suggesting that, in intact cells, HIF binds this site.
