Sentence examples for importantly altered from inspiring English sources

Most importantly, altered autonomic signalling and long QTc interval have been consistently reported in studies of shift work in humans (e.g. refs 61,62,63).

Importantly, altered acetyl-histone H3 patterns were not always linked to aberrant morphology, with many apparently 'normal' myonuclei being completely hypoacetylated, and so presumably transcriptionally inactive.

Importantly, altered DLPFC function is associated with several psychiatric conditions.

Importantly, altered transcript concentrations were accompanied by similar changes in the protein concentrations as shown for two representative examples (ANP and β-MHC).

Importantly, altered plasma clot properties in patients with low blood glucose were apparent despite administration of aspirin, statins and angiotensin converting enzyme inhibitors (ACEI), which could favorably alter fibrin clot structure and function [ 14].

More importantly, altered TGF-β signaling actively contributes to the acquisition and development of metastatic phenotypes, in part through its ability to stimulate epithelial-mesenchymal transitions (EMTs) in cancerous MECs [ 11].

Adjustment for potential covariables did not importantly alter these associations (second model).

Importantly, altering the stability of the C-terminal domain of apoE4 by the above mutations does not decrease lipid binding to that exhibited by apoE3.

Importantly, altering the function and/or abundance of any of the telomere-binding proteins affects telomere length regulation and function (i.e., prevention of a DNA damage response at telomeres).

Importantly, an ischemic challenge can significantly alter local metabolism.

Importantly, these altered patterns of DNA epigenetic marks (e.g. 5-mC, 5-hmC) are frequently accompanied by a critical imbalance in transcriptional programs involving differentiation and stem cell maintenance, thereby initiating tumorigenesis and sustaining growth (Jones and Baylin, 2007).