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The important variants in these structures are (1) the starting point and levels of first-bracket rates, (2) the top bracket or maximum marginal rates, and (3) the income range within which rates rise from the lowest to the highest levels.
Furthermore, it minimises the possibility of failing to identify important variants in hitherto unstudied genes.
Moreover, it avoids the possibility of missing the identification of important variants in hitherto unstudied genes or regions of the gene-harbouring and gene-controlling elements.
The effort performed highlighted varieties relationships and important variants in fruit key processes useful to dissect the path from sequence variant to phenotype.
However, these studies are limited by current inconsistencies in funtional inference, effects of locus heterogeneity, and they may not account for important variants in introns and/or untranslated regions [ 6].
These results show the power of XP-EHH analyses in cattle to discover promising candidate genes and raise the hope of identifying phenotypically important variants in the near future.
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The SNP in the AR gene is located in intron 4 and it is in linkage disequilibrium with important variants located in the promoter region of the gene in cattle.
In this section, we will take a look at the most important variants discovered in different populations whose promoting or protective role in BC development has been verified (Table 1).
Overall, these results might open the way towards the identification of important variants involved in adaptation to tropical conditions and in particular to resistance to tropical infectious diseases.
We included variants with potential influence in the gene and protein function, as well as the most important variants described in the literature.
Additional file 12. Comparative sample frequency of important variants found in this and other HNSCC studies.
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