Sentence examples for important unsolved question from inspiring English sources

How cells regulate autophagy under normal nutritional condition is an important unsolved question in the field.

Lastly, the analysis on such a compendium of six breast cancer datasets, might provide answers to an important unsolved question: why is there only limited overlap between existing signatures?

DOI: http://dx.doi.org/10.7554/eLife.02641.002 Cytoskeletal motor proteins transport and position a variety of macromolecules, organelles and mRNAs in the cell interior (Vale, 2003), but how these motors are themselves targeted to specific locations within the cell is an important unsolved question.

Surprise is an understatement, as the seven problems are perhaps the deepest, toughest, and most important unsolved questions in all fields of mathematics.

Economist Ernst Fehr of the University of Zurich agrees and also believes having the skill to pin down what can be answered experimentally is just as important: "an instinct for the important unsolved questions and tackling those that can be successfully tackled," says Fehr.

An important and unsolved question is whether genome-wide hypomethylation and single-copy CpG island promoter hypermethylation are two independent alterations or if they are mechanistically linked.

An important yet unsolved question from this work is how knockdown of Numb causes apical accumulation of E-cad in polarized MDCK cells in the absence of a stimulus.

While in the biological sense this is not a paradox at all, the metaphor is still useful because it allows examining of the distinction between Lamarckian and Darwinian evolution, and specifically, since it enables us to raise an important and unsolved question: "Can the phenotype affect the genotype?" or in other words, "can epigenetics translate into genetics"?

An important, as yet unsolved question is how TLS and replication checkpoint activities are coordinated at stalled replication forks to maintain genomic stability while ensuring the resumption of DNA replication.

The reconstruction of a distribution knowing only a finite number of its moments is an extremely important but in practice still unsolved question for many fields of science (chemical and process engineering, electronic engineering, nuclear physics, image analysis, biotechnology…).

This question remains an important, unsolved issue in cognitive neuroscience.