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This is one of the most important unsolved problems of mathematics.
This problem became one of the most important unsolved problems in algebraic topology.
This problem (now known as the Poincaré conjecture) became one of the most important unsolved problems in algebraic topology.
Cohen solved a problem (first on David Hilbert's influential 1900 list of important unsolved problems) concerning the truth of the continuum hypothesis.
One of the most important unsolved problems in mathematics is the Riemann hypothesis about the zeros of the Riemann zeta function, which gives a square root type error term for the number of primes in a large interval.
Three-dimensional patterns of erosion and deposition associated with sediment waves pose important unsolved problems for the dynamics of alluvial forms and the effects on aquatic and riparian ecosystems.
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Decades ago, Nobel laureate Richard Feynman '39 referred to it as "the most important unsolved problem of classical physics" — and that still holds true today.
"The souls have already departed the bodies, I think, of some of the people there, and I can only surmise that they continue living only because they have some important unsolved problem".
Of those that remain, however, one, in part, requires a solution to the Riemann hypothesis, which is usually considered to be the most important unsolved problem in mathematics (see number theory).
These diagrams are the early fruits of a new approach to the most important unsolved problem of the last century: how to make a rich country out of a poor one.
On the same question, a technical exchange among scientists is more likely to elicit a "Huh?" A conference here this month brought together both camps to explore that question -- which happens to lie at the heart of the most important unsolved problem in physics -- in the hope of bringing forth a satisfying "Aha!" of discovery.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com