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The optimal management in patients with acute kidney injury (AKI) remains uncertain and dosing of renal replacement therapy (RRT) remains an important unresolved issue in management of these patients.
The validity of synfire chains is still an active topic of debate, and an important unresolved issue surrounds their development.
Elucidation of the precise mechanisms for unregulated B-cell proliferation as a result of AID deficiency is an important unresolved issue.
Another important unresolved issue is how these agents can best be integrated into a sequential treatment plan for mCRC patients.
One particularly important unresolved issue concerns the validity of the DSM-IV distinction between inhalant abuse and inhalant dependence disorders.
An important unresolved issue regarding the use of Xpert assay to test non-respiratory samples is the differing processing requirements for each sample type.
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Important unresolved issues are identified.
Finally, we identify a number of important unresolved issues for the field.
The correlation of a material's structure with its properties is one of the important unresolved issues in materials science research.
However, several important unresolved issues related to HPV triage remain, two of which are: what type of HPV test should be used and what age group should be targeted.
However, there are important unresolved issues, including the appropriate maximum implantation time, the possibility to safely and efficaciously remove the filters without being compromised by entrapped clots, and the use of anticoagulation during the implantation and periremoval periods.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com