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In conclusion, we identified EphB1 as a novel and important trigger of early astrocyte response pathway partially through activation of STAT3, which mediates restorative processes.
Accumulating evidence has demonstrated hypoxia to be an important trigger of tumor cell invasion or metastasizes via hypoxia-signaling cascades, including hypoxia-inducible factors (HIFs).
Pollen with other factors and microorganisms, like fungal spores is an important trigger of respiratory diseases.
Starvation is an important trigger of stress responses [13] and is associated with changes in metabolic and catabolic pathways and with signs of membrane stress [14, 15].
In addition, diet is recognized in some patients as an important trigger of gut symptoms, and dietary therapeutic approaches have been recently developed, such as the low-FODMAP diet where poorly absorbed and rapidly fermentable carbohydrates are avoided [8].
The invention of the steam engine was an important trigger of this development.
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Experimental studies have shown that activation of bradykinin B2 receptor is one of the most important triggers of ischemic preconditioning.
Altered gut integrity due to increased intestinal permeability and bacterial translocation represent important triggers of sepsis and sepsis-related organ dysfunction [45].
CONCLUSIONS: Among the many biological, morphological, and social markers of increasing maturation, the visible signs of maturity are important triggers of alcohol use and AUD, especially when they occur early and in young people with conduct problems, deviant peers, problem families and inadequate parental supervision.
Introgression is a form of horizontal DNA transfer, and interspecific hybridization is one of the most important triggers of large-scale genome restructuring by natural genetic engineering.
Biomechanical stress and neurohumoral factors are considered to be the two most important triggers of cardiac hypertrophy, with neurohumoral activation primarily involved in pathological cardiac growth [36].
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