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The HER2-VIA binding sites that are both necessary and sufficient for rapid HER2 removal from the plasma membrane remain unidentified, but these sites could become future targets for small molecules or could be important to elucidation of structure-activity relationships.
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However, with this in mind, it is important to note that the elucidation of a specific physiological role for a given glycan modification, such as sialylation, poses formidable challenge.
Therefore, it is very important to measure glial metabolism in vivo for the elucidation and diagnosis of these diseases.
Elucidation of these differences is important to the discovery and utilization of genes for Brassica breeding and to shed light on Brassica evolution.
Hence, the elucidation of vector insertion mediated oncogenesis is important to ascertain the risk of gene therapy approaches utilizing integrating vectors.
Elucidation of chemical structures, especially from natural products, is important to identify potential drug candidates with fewer adverse effects and structural novelty for drug discovery [1].
Elucidation of the diverged functions of the duplicated genes is important to understand how organisms acquire phenotypic diversity during evolution.
The elucidation of etiology and pathophysiology of the disease is extremely important to establish treatment and prevention strategies [ 30].
It is likely that elucidation of the expression patterns of muscle-specific sarcomeric proteins is important to understand muscle disorders originating from defects in contractile sarcomeric proteins.
Elucidation of additional necroptosis signaling mechanisms downstream of necrosome assembly will be important to fully understand how necroptosis is regulated in neuronal cells.
A better quantitative understanding of this regulation is likely to be important for elucidation of the melanocyte biology.
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CEO of Professional Science Editing for Scientists @ prosciediting.com