Sentence examples for important target tissues from inspiring English sources

Human oral mucosal cells are important target tissues for regenetic engineering and are sources of epithelial sheets.

This chapter discusses lentiviral vectors design and function and discusses recent advances that improve their biosafety and demonstrate their potential for gene delivery into important target tissues of gene therapy.

We analyzed the effects of stress on the transcriptome in the brain and kidney, which are considered important target tissues along with muscle, blood cells, liver and epithelia.

Our current study reveals several candidate genes as well as important target tissues on which to base new targeted hypotheses to be tested in the future.

Since important target tissues of TTR load belong to the ANS and PNS, the aim of the present study was to investigate TTR localization in tissues and cells of these systems.

In an attempt to identify mechanisms that could have been responsible for the differential impact of the treatment with GH + T4 vs. GH alone on longevity, we have examined expression of a number of genes related to GH, IGF-1 and insulin signaling in the skeletal muscle and WAT, important target tissues for these hormones.

Recent studies have suggested that, in addition to adipose, liver and muscle tissue, the osteoblast is also an important target tissue for insulin action [ 16, 17].

In brief, formidable strides have been made in biochemistry specific to this important target tissue, despite the inability to acquire tracheobronchial epithelium in large quantities.

Bone is an important target tissue in patients with RA, with many patients developing local erosions and periarticular and generalised osteoporosis.

Here, the authors use metformin-treated rat cardiomyocytes as a model to assess the effects of metformin on this important target tissue, focusing on the role of ERSS.

Liver is also the most important target tissue for detoxifying processes and the depletion of xenobiotic metabolism is also one of the potential ways to reduce ROS production [ 69].