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An important target tissue for murine cytomegalovirus (CMV) infection is the submaxillary salivary gland.
The pleura is an important target tissue of fiber-induced disease, although it is not known whether fibers must be in direct contact with pleural cells to exert pathologic effects.
In brief, formidable strides have been made in biochemistry specific to this important target tissue, despite the inability to acquire tracheobronchial epithelium in large quantities.
Recent studies have suggested that, in addition to adipose, liver and muscle tissue, the osteoblast is also an important target tissue for insulin action [ 16, 17].
Bone is an important target tissue in patients with RA, with many patients developing local erosions and periarticular and generalised osteoporosis.
Here, the authors use metformin-treated rat cardiomyocytes as a model to assess the effects of metformin on this important target tissue, focusing on the role of ERSS.
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Human oral mucosal cells are important target tissues for regenetic engineering and are sources of epithelial sheets.
This chapter discusses lentiviral vectors design and function and discusses recent advances that improve their biosafety and demonstrate their potential for gene delivery into important target tissues of gene therapy.
Our current study reveals several candidate genes as well as important target tissues on which to base new targeted hypotheses to be tested in the future.
We analyzed the effects of stress on the transcriptome in the brain and kidney, which are considered important target tissues along with muscle, blood cells, liver and epithelia.
Since important target tissues of TTR load belong to the ANS and PNS, the aim of the present study was to investigate TTR localization in tissues and cells of these systems.
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