Sentence examples for important substrate of from inspiring English sources

PARP is the most important substrate of caspase-3, which is associated with DNA repair and monitoring of genetic integrity.

E-cadherin is an important substrate of MMPs, as its cleavage not only helps separate tissues into individual cells but also induces signaling supportive of EMT.

Unfortunately, glucose concentration in the Extra-Cellular Fluid (ECF) is only 5 mM, and the concentration of molecular oxygen, another important substrate of the GBFC, is markedly lower in blood (45 µM) than in aqueous solutions under air (200 µM).

Recent studies show mTOR is an important substrate of Akt.

Most importantly, they do not affect the processing of an important substrate of γ-secretase, Notch.

The accumulation of small, even miniscule, ischemic lesions is an important substrate of SVD 60.

Substrates of nucleophiles are commonly alkyl halides, while aromatic compounds are among the most important substrates of electrophiles.

Some of the important substrates of CYP3A4 include macrolide antibiotics, anti-arrhythmics, antidepressants, anxiolytics including alprazolam, midazolam and diazepam [8], immune system modulators and an array of calcium channel blockers.

Polycyclic aromatic hydrocarbons and their dihydrodiols are important substrates of CYP1B1 (Oesch-Bartlomowicz and Oesch 2007).

The ribosomal protein S6 kinases are also important substrates of mTOR.

The Akt-mediated phosphorylation inactivates GSK-3β, which leads to the accumulation and nuclear translocation of β-catenin, one of the most important substrates of GSK-3β 31.