However, we believe that random variation, both technical and biological, is the most important source of differences between biomarker patterns describing the same pathophysiological process.
We observed changes in coding exons and promoter sequences throughout the Meg gene array in maize, consistent with a model in which mistakes introduced during the production of tandemly-duplicated gene arrays may be an important source of differences in both gene expression and protein function.
Apart from the somewhat different populations studied (our projections were based on rates from GB, not just England (86.2% of the British population in 2007)), the availability of 4 years additional data (2004 2007) and the slight differences in methodology, there are two important sources of difference.
It was recently argued that sexual conflict might be an important source of sex differences in ageing [8], [12].
The specific outbreak scenario was still an important source of performance differences, with the size of the outbreak having a greater impact on performance differences between algorithms than the extent of clustering.
Porter explains why trade-offs are an important source of profitability differences among rivals, and why trade-offs make it difficult for rivals to copy what you do without compromising their own strategies.
The way they do this has long been recognised as an important source of the differences in people's responses to drugs.AXYS has been running computer models of trials of drugs metabolised by the complex.
However, our findings do not support health-related selection as an important source of socioeconomic differences in adult cardiometabolic health.
Based on our estimates of multivariate effect size, allometry provided the most important explanatory source, with fragmentation status representing the second most important source of variation; differences between species and islands were slightly smaller in magnitude.
This was unexpected and suggests that mutations that are not corrected by mismatch repair are an important source of the genetic differences found between different humans, and between humans and their ancestors.
