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The most difficult applied problems are those for which different scales are important simultaneously.
Analytical models of HIV-1 evolution with recombination allow description of viral evolution not only at the extremes of very small and very large Ne, where drift and selection, respectively, dominate, but also at intermediate values of Ne where both selection and drift remain important simultaneously [24], [27], [28], [31], [33]-[35].
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Thus, it is important to simultaneously enhance antitumor and anti-metastasis efficacy.
In the aftermath of the Wall Street protests, we should definitely mobilise people to make such demands – however, it is no less important to simultaneously remain subtracted from the pragmatic field of negotiations and "realist" proposals.
As you may have noticed, some planning models can be quite complex, since in today's planning environment it is important to simultaneously consider multiple objectives and constraints.
To understand the role of l-arginine depletion in impaired nitric oxide synthesis in disease, it is important to simultaneously quantify arginine, citrulline, and ornithine in the plasma.
The aspect of this crisis that is probably the most important and simultaneously the most difficult to recognize is that the heroic efforts needed to alleviate it will not come from the government or the wider American society.
It is very important to simultaneously ignite all the outer surfaces of explosive 3.
It is very important to simultaneously ignite all fuses 2 of explosive 3.
In particular, it is important to simultaneously solve the unknown function and its derivatives with high-order accuracy.
Another approach is to accurately evaluate the impact of the independent variables on the dependent variables by varying all the important factors simultaneously in a systematic manner.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com