Sentence examples for important signalling pathways from inspiring English sources
MAPK cascades, which consist of MAPKKK, MAPKK and MAPK, are among the most important signalling pathways and are activated by R genes39.
They influence the morphology of the microtubule cytoskeleton, function as the base for the primary cilium and serve as a nexus for important signalling pathways.
GSEA and IPA uncovered important signalling pathways enriched in basal cells including TGF-β, NOTCH, WNT/TCF, IGF, FGF, STAT3/IL6 and others (Supplementary Fig. 1e and 3a c; and Supplementary Data 2).
Thus this book is an excellent summary of important signalling pathways in cancer that will be useful for students and researchers.
We focused on ERK and PI3K that are most important signalling pathways involved in cell growth.
Using a data mining approach we have identified that genes involved in the normal processes of the ovarian cycle may constitute potentially important signalling pathways involved in ovarian cancer.
Although we cannot disregard other, off-Notch, effects in integrin modulation and BM-PC adhesion and differentiation, our data strongly suggests that this important signalling pathway is involved.
The retrograde response constitutes an important signalling pathway from mitochondria to the nucleus which induces several genes to allow compensation of mitochondrial impairments.
We and others previously showed that PI3K/Akt is an important signalling pathway involved in the control of osteoblast survival [24], [46], [49], [50].
