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Still, it is important to bear in mind that the use of steel mechanical fasteners involves making a hole on the SS strip which may lead to an important setback due to the reduction of the SS cross section of the strip to install the fasteners.
As a consequence of the battle's outcome, the leaders of the main families of the Southern provinces lost faith in Orange's cause and the promises of aid made by the English queen Elizabeth I, which meant an important setback to Orange.
Shortage of research funding was mentioned as the most important setback to health research in MRCs and HRIs.
An important setback of our study is that it is a case-control study with a very high proportion of patients compared with controls, when in a screening setting for glaucoma the prevalence of the disease would be much lower.
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Hague says the opposition has had important setbacks.
More recently the institute has suffered some important setbacks that suggest that its influence has been waning.
Not only did the epidemiological transition start late in Antananarivo, it also proceeded by fits and starts, with important setbacks, particularly in the mid-1980s.
From a theoretical perspective, Antananarivo has experienced mortality falls, reversals and stalls over time, with important setbacks particularly in the mid-1980s and the coexistence of infectious diseases and nutritional deficiencies with non-communicable diseases.
"She started out with this very important personal setback, which was her mother saying, 'You're my ugly little monster,' " Ms. Immordino Vreeland said.
When I look back at it I realise how important these setbacks were.
Probably, one of the most important military setbacks for Isis in recent weeks was the loss of al-Houl, a town captured by the Syrian Kurdish People's Protection Units (YPG) on 13 November.
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