What has been left out of the debate thus far are two important secondary effects of estate taxes.
Institutional factors such as the need for legal separation between government and industry created important secondary effects that drove the particular forms in which project management evolved.
Moreover, this hypoxia-modulated interaction may be of clinical relevance for response to anti-angiogenic therapy-mediated induction of hypoxia that has been shown recently to invoke important secondary effects triggering massive tumor invasion [47].
There would be significant secondary effects, too.
While all data agree that PINK1 exerts an important, but possibly secondary effect on mitochondrial bioenergetics, the function of PINK1 for mitochondrial dynamics, fragmentation and degradation appears less prominent in mouse tissue.
The primary outcome was change in IQ, but important secondary outcomes were effects on markers of glomerular and tubular kidney function: urinary excretion of albumin, alpha-1-microglobulin (A1M), γ-glutamyl transpeptidase (γ-GT), and N-acetyl-β d-glucosaminidase (NAG).
This result indicates that a secondary effect is important in addition to conformation-mediated activity reduction of Cel5A.
2 If we have reason to view one effect (which I will call the primary effect) as more fundamental or more important than the other (the secondary effect), we could use a hierarchical approach.
This wide range of concentrations may be due to the effect of important secondary factors.
Hence, it is important to consider secondary effects when analyzing miRNA overexpression datasets.
