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Important randomized controlled studies have been published in "healthy" smokers (primary prevention); patients with early lesions, such as mucosal dysplasia/metaplasia (secondary prevention); and those who have already had definitive treatment for their first tobacco-related malignancy (tertiary prevention).
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Despite these confounding factors, the study allowed to collect very positive initial data to ascertain the safety of the technique posing important basis for the future randomized controlled study.
In the 1920s statistician and biologist Ronald Fisher discovered the most important principles behind A/B testing and randomized controlled experiments in general.
Although a prospective, randomized, controlled trial with important outcome measures is necessary to draw conclusions about this therapy, data from infants with PPHN have clearly helped to frame the important questions about this novel therapy.
Randomised controlled trial OR randomized controlled trial.
Hammer says he understands Delfraissy's perspective but says randomized, controlled trials did play an important role in the history of HIV drug development.
One important limitation of our study is the lack of a randomized, controlled trial design.
RCT, randomized controlled trial.
To answer this question we needed randomized, controlled research.
Prospective randomized controlled trial.
Blinded randomized controlled trial.
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