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Paxillin, an important protein component of the cell-matrix adhesion, was completely absent from focal adhesions and focal contacts in Hakai-overexpressing MDCK cells.
A sufficient intake of Vitamin C is essential for the formation of mature collagen, which in turn is an important protein component in connective tissues such as skin, cartilage, and bone (Stuart-Macadam, 1989; Hirschmann and Raugi, 1999).
Connexin 43, encoded by the gene Gja1, is an important protein component of gap junctions, is detected at day 11.5 in somatic cells of the undifferentiated mouse gonad (after migration of germ cells but before sexual differentiation), and is later localized at the interface between somatic and germ cells (85).
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While such investigations have shed light on important protein components of CM, a paucity of information exists regarding the metabolite component of CM.
Important protein components of caveolae are cavins and caveolins.
As the most important protein components of chromatin, histones have been extensively studied.
We also investigated the characteristics of PmNV polyhedrin, which is a functionally important protein and the major component of the viral OBs (occlusion bodies).
These include important proteins including the SecE component of the translocon and members of the bacterial serine/threonine (ser/thr) protein kinase family.
It is critically important to increase our understanding on protein components of pathogens and vaccines as well as cellular and host responses to infections and vaccinations.
The study of cellular structures in the presence of antibodies targeting their protein components can provide important information about intrinsic characteristics of the structure of interest [ 23– 25].
Among these, several hair shaft keratins (Krt31– Krt86) and keratin-associated proteins (Krtap1– Krtas25) as well as the S100a3 protein, an important structural component of the hair cuticle (Kizawa et al, 1998), were found to be strongly diminished in their expression in mutant epidermis.
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