However, the individual reviews and the consultative process that followed uncovered important problems concerning the interpretability of the data and the validity of the conclusions drawn.
Among the most important problems concerning public health services in Greece were long waiting times in hospitals (n=115, 60.2%), difficulties in communication with health professionals (n=87, 45.5%), high cost of health care (n=74, 38.7%) and system's complexity (n=65, 34%).
From the technical point of view, there is an important problem concerning composition of logics known as the collapsing problem, first identified in Gabbay 1996b, and later formalized in del Cerro and Herzig 1996.
This study is directed towards an important problem concerning the organization of the peptidyl transferase center (PTC) on the mammalian ribosome that cannot be studied by X-ray analysis since crystals of 80S ribosomes are still unavailable.
Microbial production of butanol by solventogenic Clostridium has long been complicated with the formation of acetone as an unwanted product, which causes poor product yields and creates a most important problem concerning substrate transformation.
Cataract, which is the most frequent late complication of trabeculectomy, constitutes an important problem concerning, according to different sources, from several to several dozen per cent of patients after a filtering surgery [ 12, 13].
An important problem concerning these species was the very large amount of missing data in our concatenated alignments (>50% in the complete data set of 70 proteins), in agreement with their very small genome sizes (especially for N. equitans, with only 540 protein-coding genes, and Micrarchaeum and Parvarchaeum, with approximately 1,000 protein-coding genes).
Damage effects analysis and assessment of buildings under blast loading is an important problem concerned by the area of explosion accident analysis, blast-resistant design, anti-terrorist and military weapon design.
One more important problem concerns the potential of false positive tests.
Cohen solved a problem (first on David Hilbert's influential 1900 list of important unsolved problems) concerning the truth of the continuum hypothesis.
