We can come across stochastic behavior while examining many important problems of a global character in various fields of research, for example, in the theory of climate change.
Reviewer 1: Mikhail Gelfand, Department of Bioengineering and Bioinformatics, Moscow State University, and Institute for Information Transmission Problems RAS, Moscow, Russia The paper addresses an important problem of selecting a good similarity measure for comparing gene expression patterns.
Motivation:Despite recent advances of modern GWAS methods, it is still remains an important problem of addressing calculation an effect size and corresponding p-value for the whole gene rather than for single variant.
For the clinically important problem of determining whether a given primary tumor will metastasize, tree level features show improved prediction accuracy by at least 3.5% over all other feature sets considered, including comparable feature sets from the earlier unweighted models.
This paper addresses an important problem of integrating structural optimization into a traditional CAx system and therefore, realizes an integrated product design-optimization system.
Level set methods are versatile and extensible techniques for general front tracking problems, including the practically important problem of predicting the advance of a fire front across expanses of surface vegetation.
This solution is generalized, using Happel's free-surface model, to cover the practically important problem of flow relative to a swarm of permeable spheres.
This paper addresses an important problem of such systems: how to construct an optimal publish/subscribe tree for routing information from the source to all interested recipients.
Nevertheless, it represents a rough approach to an important problem of the relative structure of capital; that is, of the proportions in which goods of various kinds are found.
In such machine learning approaches, the important problem of feature selection equates to a problems of relevance.
