Pulmonary hypertension in the postnatal period due to this condition is an important problem, since currently nearly 140 million people reside at over 2,500 meters above sea level, being permanently exposed to chronic hypoxic conditions (34, 41).
In this context, this study represents valuable preliminary work, indicating important problems with currently promoted PSA-based criteria, which need to be addressed now for men whose prostate cancer is currently being managed by monitoring (Donovan et al, 2003; Hardie et al, 2005; Klotz, 2007; van den Bergh et al, 2007).
Motivation: Understanding gene regulation in biological processes and modeling the robustness of underlying regulatory networks is an important problem that is currently being addressed by computational systems biologists.
Despite being an important class of search problem, currently little is known about how searchers maximize the chances of finding targets in these situations.
The protocol is registered in the ClinicalTrials.gov register (NCT00928863) This study addresses an important problem because PPH is currently the major cause of severe maternal morbidity in the Netherlands.
Uncertainty management for geometric data is currently an important problem in spatial databases, image databases, and geographic information systems.
An important problem regarding the majority of currently available literature that reports on revascularisation strategies for PAD is that it does not focus on CLI patients specifically and studies them as a minor part of the complete cohort.
As such, the possible influence of temperature on the tectonic tremor activity is currently an important problem under discussion in the field of seismology.
Motivation: Developing methods for computing phylogenetic networks from biological data is an important problem posed by molecular evolution and much work is currently being undertaken in this area.
Currently, real-time and quantitative evaluating the effectiveness of VSR is an important problem.
