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This study is directed towards an important problem concerning the organization of the peptidyl transferase center (PTC) on the mammalian ribosome that cannot be studied by X-ray analysis since crystals of 80S ribosomes are still unavailable.
Microbial production of butanol by solventogenic Clostridium has long been complicated with the formation of acetone as an unwanted product, which causes poor product yields and creates a most important problem concerning substrate transformation.
From the technical point of view, there is an important problem concerning composition of logics known as the collapsing problem, first identified in Gabbay 1996b, and later formalized in del Cerro and Herzig 1996.
Motivation: Understanding the association between genetic diseases and their causal genes is an important problem concerning human health.
An important problem concerning poultry production in Africa is the high cost of feed ingredients particularly: grains, protein concentrate and vitamin-mineral premix.
Cataract, which is the most frequent late complication of trabeculectomy, constitutes an important problem concerning, according to different sources, from several to several dozen per cent of patients after a filtering surgery [ 12, 13].
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Damage effects analysis and assessment of buildings under blast loading is an important problem concerned by the area of explosion accident analysis, blast-resistant design, anti-terrorist and military weapon design.
One more important problem concerns the potential of false positive tests.
The United Nations resolution (44/225) on large scale pelagic driftnets has highlighted some important problems concerning these fisheries.
However, the individual reviews and the consultative process that followed uncovered important problems concerning the interpretability of the data and the validity of the conclusions drawn.
Among the most important problems concerning public health services in Greece were long waiting times in hospitals (n=115, 60.2%), difficulties in communication with health professionals (n=87, 45.5%), high cost of health care (n=74, 38.7%) and system's complexity (n=65, 34%).
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