Sentence examples for important phenotypic changes from inspiring English sources
Some really important phenotypic changes, like DDT resistance in insects are sometimes caused by single mutations.
As their concentration rises, the autoinducers activate transcriptional regulators that trigger important phenotypic changes in the cells.
To conclude, this study shows that the sequence variations in vivo, occurring during a limited number of bacterial generations, give rise to important phenotypic changes in the bacteria and have a direct impact on the adaptation of the bacteria to its host.
During subculture the LM38 cell line acquired important phenotypic changes.
Structural variations are the main source of genomic variation, having been associated with important phenotypic changes, including several rare and complex diseases in humans [ 27].
In addition to revealing the power of human selection to cause large-scale shifts in gene expression patterns, these data facilitate the prediction of processes that underlie important phenotypic changes in the fibre of domesticated cotton.
Conclusion: These findings are consistent with the hypothesis that altered expression of enzymes essential for in situ retinoic acid biosynthesis is an important phenotypic change associated with the development of endometrial cancer.
Regulation of the tumour cell cytoskeleton to facilitate invasion is also an important phenotypic change in metastatic tumour cells.
We reasoned that such features might be important because phenotypic changes in cell behavior can arise from integrated signal processing, as well as from the relative level of signal activation34,35,36.
One of the most important intracellular phenotypic changes of the MCF-7 stable cell lines and lymphoblastoid cells harboring patient PTEN ATP-binding mutations is the predominant nuclear localization, which is accompanied by decreased G1/S ratio and apoptotic rate when compared with the PTENWT cells (9).
Based on this analysis, we surmised that alterations in AKT and/or MAPK signaling pathways may play an important role in phenotypic changes induced by JCV T-Ag transfection in CRC cells.
