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We hypothesized that alterations in gene expression could identify important pathways involved in transplant lung injury.
The MAPK pathway is identified as one of the most important pathways involved in cell proliferation and differentiation.
The MAP kinase pathway is one of the most important pathways involved in cell proliferation and differentiation, and its components are promising targets for antitumor drugs.
Furthermore, with the availability of such models, not only important pathways involved in cell dysfunction may be better understood, but also drug targets predicted based on these models can be seen as novel targets for in vivo validation.
TGFβ signaling [24] and hedgehog signaling [25] are important pathways involved in regulating cell growth.
These results strengthen once again that ABA and cold acclimation are probably the most important pathways involved in ecodormancy regulation.
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P38 MAPK (Mitogen-activated protein kinase) is an important pathway involved in diverse biological processes.
Blockade of the hedgehog (Hh) signaling pathway, an important pathway involved in stem cell self-renewal, by cyclopamine leads to long-term prostate cancer regression without recurrence, strongly suggesting the connection between Hh pathway and prostate CSCs.
MEK/Erk is another important pathway involved in autophagy.
FGF/FGFR signaling is also an important pathway involved in the maintenance of adult bone homeostasis.
15 This is a key observation, because NFκB is a critically important pathway involved in both innate and adaptive immunity.
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