Taeniosis and cysticercosis caused by adult and larval stages of the Taenia solium (Platyhelminthes: Cestoda, Cyclophyllidea, Taeniidae) parasite, respectively, remain important parasitic diseases and a major health and economic burdens in less developed countries.
Human schistosomiasis caused by blood fluke parasites of Schistosoma genus, remains an important parasitic disease and a major health economic problem in many tropical and subtropical countries.
The Sti1-binding motif in Leishmania Hsp90 is suboptimal – optimizing the motif increased initial intracellular proliferation underscoring the importance of the Hsp90 Sti1 interaction for this important parasitic protozoan.
An important parasitic form is Histomonas meleagridis, the cause of enterohepatitis (or blackhead) in poultry.
Orobanche ramosa is an important parasitic weed of several agriculturally important crops.
Coccidiosis of chickens is one of the commonest and economically most important parasitic diseases of poultry worldwide.
Nifurtimox and benznidazole represent the only treatments options available targeting Chagas disease, the most important parasitic infection in the Americas.
Currently, DNA vaccination against such important parasitic diseases like malaria, leishmaniosis, toxoplasmosis, cryptosporidiosis, schistosomosis, fasciolosis offers several new opportunities.
Recommendations aimed at limiting the development of anthelmintic resistance by reducing treatment intensity raises a simultaneous demand for reliable and accurate diagnostic tools for detecting important parasitic pathogens.
Supported by studies in the free-living nematode, Caenorhabditis elegans, some recent investigations have provided improved insights into selected protein phosphatases (PPs) of economically important parasitic nematodes (Strongylida).
In the present article, we compiled transcriptomic data sets of key, socioeconomically important parasitic helminths, and constructed and validated a curated database, called HelmDB (www.helmdb.org).helmdb.org
