Liver is the most important organ, which plays a pivotal role in regulating various physiological processes in the body [ 1].
Moreover, the ramie bast fiber, involved in sugar metabolism and cellulose synthesis, is an important organ, which has the value of biological research for organogenesis and evolution.
Therefore, not only the system regulating their production is important, but also organs which contribute to their elimination.
John Hayward of Human Events counters that Mr Huckabee was correctly identifying what he sees as the condescending way that Democrats treat women: "The entire passage is his firm statement that he thinks women are 'smart, educated, intelligent, and capable,' and he's advising the Republican Party - an important organ of which he was addressing - to treat them as such".
Visceral adipose tissue is an important functional organ which abundantly secretes adipocytokines [ 33].
Adipose tissue has been demonstrated to be an important endocrine organ which secretes cytokines and regulatory factors.
Because adipose tissue is an important endocrine organ, which secretes adipokines or cytokines that regulate inflammatory responses and metabolic homeostasis, aberrant adiposity dysregulates adipokine levels and leads to a variety of metabolic disorders and complications, such as diabetes and cardiovascular diseases.
Despite the knowledge that ionizing radiation effectively causes DNA damage, numerous reports suggest the existence of complex intracellular and inter-cellular damage signaling pathways in cells, tissues and organs which exert important biological effects [1], [2].
Multiple signal transduction pathways converge on Wnt/β-catenin signaling to mediate cell proliferation, differentiation and development in a variety of tissues or organs, which plays important roles in generation of tissues, including skin [ 38, 39].
The variability of gene expression in equivalent human and minipig tissues is considerably higher in minipig organs, which is important for study design in case a human target belongs to this variable category in the minipig.
