uORF length has been shown to be important; short open reading frames or those that have been translated more quickly favour translation reinitiation downstream [ 11, 78, 79], possibly by the remaining association of translation inititiation factors with the ribosome [ 80, 81].
Therefore, it would appear that structural dynamism rather than mutational rate is more important for constructing novel open reading frames in the mitochondrial organellar genome of Arabidopsis thaliana.
Following transcription elongation, nucleosome deacetylation is important to prevent spurious transcription initiation within the open reading frame (ORF) [5], [6], [7].
Surprisingly, genes where function and orthology were unknown were also not different from the null expectation, suggesting that many of these open reading frames are not functionally important.
A quantitative description of the relationship between protein expression levels and open reading frame (ORF) nucleotide sequences is important for understanding natural systems, designing synthetic systems, and optimizing heterologous expression.
One important translational control signal found in both prokaryotes and eukaryotes is the upstream open reading frame (uORF), a small open reading frame located upstream of the main coding region [ 11].
Hos2, a class I HDAC enzyme plays an important role in gene activation in the yeast Saccharomyces cerevisiae by binding to open reading frames (ORFs) of active genes.
GABAB1j open reading frames (ORF) and expression patterns are not conserved across species, and they do not have any important functional domains except sushi domains.
Small open reading frames.
