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Unnecessary complexity and delay in the procedures for granting rights of way may therefore represent important obstacles to the development of competition.
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Poor permeability and selectivity of the cell membrane are an important obstacle to the development of peptide drugs and therapeutic proteins [ 136] because of the endothelium, which is the first physiological barrier between blood and tissues.
Mr. Reagan was concerned about unreasonable obstacles to the development of deep seabed mineral resources.
Wales's highly variable relief and climate are obstacles to the development of other commercial crops.
All of these present formidable obstacles to the development of novel therapeutic approaches to AD.
Absorption windows in the proximal gut can limit the bioavailability of orally administered compounds and can be a major obstacle to the development of controlled release formulations for important drugs.
Currently, our incomplete understanding of the adhesion mechanisms important in the most life-threatening clinical forms of malaria is a major obstacle to the development of adjunctive therapies.
A major obstacle to the development of education software is its enormous cost, said Mr. Heuston.
But a potential obstacle to the development of irrigation is the cost.
A major obstacle to the development of effective treatments is the absence of reliable animal models.
Vector control offers an important means of limiting the spread of malaria; however, the lack of genetic information on Plasmodium-susceptible anopheline mosquitoes is a major obstacle to the development of effective vector management.
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