Sentence examples for important negative feedback from inspiring English sources

In addition, we present data that suggest that phosphorylation of Elm1 by Cdc28 is an important negative feedback event leading to degradation of Elm1 upon completion of mitosis.

For ligand-independent ER activation, control of phosphorylation at this site may provide an important negative feedback function on transcriptional activity and consequently on the chromatin structure at the promoter level in ER ligand-independent activation.

Elimination of APCs provides an important negative feedback to limit T-cell-mediated immune responses.

An important negative feedback mechanism is given by the neuronal M2 muscarinic receptor that inhibits acetylcholine release [ 3, 4].

Notably, IκBα and A20 are important negative feedback regulators of NF-κB signaling and are crucial for damping the proinflammatory activity.

Thus, we uncover an important negative feedback regulatory loop that controls pro-inflammatory signalling in endothelial cells that may impact vascular inflammatory diseases.

However, in addition, there are a number of important specific negative feedback systems in place that prevent excessive elevation of body temperature.

Positive feedback is equally as important as negative feedback.

The neuromodulatory function of peptides that alter food intake is supported by their ability to recruit the activation of neurons at multiple central nodes of the gut brain axis and to affect the neural processing and behavioral potency of meal-related gastrointestinal signals important in the negative feedback control of meal size.

Generally speaking, at each stage the Earth system can be described by N important positive or negative feedback mechanisms, where by 'important' we mean the number of processes that must be included in order to accurately reproduce the dynamics.

Here it activates target genes, one of which is the suppressor of cytokine signaling 1 (SOCS1), an important mediator of negative feedback.