Sentence examples for important molecular target from inspiring English sources

Pan, J. RNA polymerase an important molecular target of triptolide in cancer cells.

Tubulin is an important molecular target in cancer chemotherapy.

The ubiquitin proteasome complex is an important molecular target for the design of novel chemotherapeutics.

Here we show that Janus kinase (JAK) 3 is an important molecular target for treatment of autoimmune insulin-dependent (type 1) diabetes mellitus.

The HIF-1α subunit, which is regulated by O2-dependent hydroxylation, ubiquitination, and degradation, has been identified as an important molecular target for cancer therapy.

Given the striking correlations between telomerase activity and proliferation capacity in tumor cells, telomerase had been considered as a potentially important molecular target in cancer therapeutics.

Dr. Monje also established new in vitro and in vivo models for studying the disease and identified important molecular targets of therapy.

Additionally, DENV infection induces expression of AAK1 transcripts, but not GAK, via single-cell transcriptomics, and these kinases are important molecular targets underlying the anti-DENV effect of sunitinib and erlotinib.

The results of microarray analysis suggested that ABCG1 and SREBF1, which were involved in the cholesterol biosynthetic and metabolic processes, and CYP17A1, NR4A2 and G6PD, which were related to aldosterone biosynthesis, were important molecular targets.

Extracellular 5-HT concentrations are regulated by 5-HT transporters (SERTs), indicating that these transporters may be important molecular targets underlying individual differences in impulsivity and drug abuse vulnerability.

Protein kinases (PKs), which play critical regulatory roles in the cellular signal transduction pathways, have been regarded as important molecular targets for clinical diagnosis as well as pharmaceutical development.