Last but not least, important modifications of the pathways result from post-translational interactions that are independent of the changes at the mRNA level.
Following this line of reasoning, it is probable that novel approaches to coping with mammographic surveillance for BC survivors will emerge from some important modifications in the conventional screening procedure that are underway, such as the early rescreen practice and the implementation of breast units, or are still undergoing research, such as the hypothesis of risk-tailored screening.
Because the scales at which mating and density-dependent regulation occur are key factors for population dynamics and evolution [ 35], we here present a new model introducing important modifications: mating sites are independent from nesting sites, and population regulation may occur either within nesting sites (hereafter named HABITAT model) or at the level of the whole population (TOTAL model).
We can see how these three important modifications of Kant's philosophy stem from the same basic concern with rational autonomy.
The most important modifications to the questionnaire that arose from this stage were 1) rearrangement of the sequence of items to make the interview more fluent, 2) rewording of questions, 3) addition of response categories, and 4) elimination of items that showed no variation.
The surface is veneered with soils, related in composition to the rocks from which they formed, but with important modifications because of the smaller grain size, the presence of organic matter, and an intricate complex of living organisms.
Important modifications to the peptide structure serve to delay its absorption from subcutaneous tissue, make it resistant to DPP-4 degradation, and enable reversible binding to albumin.
Kidneys from sham-operated rats did not show evidence of important modifications with respect to the controls (data not shown).
The early behaviourists, beginning with Watson, espoused essentially the same formulation but with some important modifications.
This definition cannot be applied without important modifications.
