Sentence examples for important modification for from inspiring English sources
The fact that several kinases can phosphorylate Serine 46 suggests that this may be a very important modification for the regulation and function of p53.
In those studies, there is increased DNA-binding activity by EMSA in response to drug treatment, but no change is identified in the level of phosphorylated p65 at the serine 536 residue [11], [12], which has been established as a important modification for NF-κB transcriptional activity [1].
In sum, these data support Lys ubiquitination as an important modification for phosphorylation of CIITA by ERK1/2.
Also, the phosphorothioate chemistry, which was developed by Fritz Eckstein, remains a highly important modification for most of today's ON drugs, since it both confers protection against degradation and aids in the cellular uptake of ONs.
Regardless of the upstream signaling cascades involved, it is increasingly clear that ER phosphorylation at Ser305 represents an important modification for ligand independence and/or tamoxifen resistance in breast cancer cells.
We have identified a novel ubiquitin (Ub) Lys linkage on CIITA IF3 and further show that Lys ubiquitination is an important modification for changing the subcellular localization and thus activity of the MHC II master regulator.
Cook brought out the first binaural records, invented a new cutting head, & has devised a number of important modifications for sound equipment.
Such an distant effect is not so evident in case of membrane rupture suggesting (since mechanical effect become global) important modifications for the cytoskeleton between the two types of stress studied.
Our findings provide evidence for an important modification of the intestine resulting from a probiotic treatment, and indicate its contribution to improvement of host serum lipids.
Increased physical activity has been recommended as an important lifestyle modification for the prevention and control of hypertension.
