Our study has important limitations, including a relatively limited population cohort size, of which 11% of women were found to have endometriosis, and possible selection bias arising from the use of telephone directories for defining the population cohort recruited from California.
Although there are many strengths to the multilevel, mixed methods approach used in this study there are also important limitations including the small sample sizes, a limited geographical focus and reliance on household rather than individual level dietary intakes.
However, this study also has some important limitations, including that the analysis of serotypes was limited to 4 of the known Vsp serotypes of the HS1 strain of B. hermsii, that we did not study any of the Vlp serotypes, and that the clinical phenotype was studied in groups of only 4 SCID mice each.
The study was successful in adding to the limited data on AOM in Thailand, but there are important limitations, including few cases in the youngest children, small sample size and lack of a clear population denominator.
While seeking to reassure customers, investors and employees that its business is healthy, Nortel said in a statement that previous revisions of its statements for the last three years were subject to a number of "important limitations," including work to be done on a detailed review of the second half of 2003.
Although iPCR have been designed to detect many proteins [10 19], it may suffer from important limitations including complicated protocol as well as requirement of special instruments and well-trained laboratory personnel.
Despite a large sample size, this study suffered important limitations, including a retrospective and single-center design, the use of an arbitrary cutoff point to define fresh and old blood, and the absence of adjustment for some important confounding factors[60].
Our study has important limitations, including a small sample size.
This study has several important limitations including its small sample size and retrospective design.
However, the methodology does have several important limitations including the inability to isolate by culture.
However, NGAL has important limitations, including its responsiveness to a variety of inflammatory conditions [ 3].
