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Cyanobacteria are an important group of photoautotrophic bacteria that have been engineered and used to produce a wide range of biomaterials and biofuels, which are usually derived from important intermediates of the central metabolic pathways.
Ab initio density functional calculations in the local spin density and Hubbard U approximations have been performed to investigate the formation of some important intermediates of the O2 photoreduction at the (1 0 1) TiO2 anatase surface as well as to compare with previous local density approximation results.
MDA, as one of the most important intermediates of free radical damages [8], [17], can readily and widely bind or crosslink important biological macromolecules such as proteins and nucleic acids [8], [18].
In wild-type colonies, many end products and important intermediates of gluconeogenesis are detected at higher levels than in colonies formed by csgD deletion mutants.
Because acyl-CoAs represent important intermediates of lipid metabolism that are affected in cancer [ 29], we report the concentrations of both long-chain as well as short/medium-chain acyl-CoAs from the liver tissue.
Properties of the HIV RNP assembly pathway elucidated here present opportunities for antiviral strategies that could block the nuclear export step of HIV replication by targeting important intermediates of the Rev-RRE complex (Fenster et al., 1994; Chapman et al., 2002; Shuck-Lee et al., 2008; Ward et al., 2009).
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The UDP-hexose B is an intermediate of lactose metabolism, and citrate is an important intermediate of Krebs cycle related energy processes.
With their new ultrafast X-ray source, the researchers are able to characterize and distinguish between the structure of the electron clouds and atomic arrangement in the critically important intermediate of photoexcited CHD that eventually leads to ring opening.
Malate, as an important intermediate of the TCA cycle, plays multiple roles in cell metabolism.
Chalcone, an important intermediate of flavonoid synthetic pathway, has been shown to exhibit diverse biological and pharmacological activities such as anti- cancer, antioxidant, anti-inflammatory, etc.
Taking an animal model approach to exploring possible metabolic contributions to the pathogenesis of autistic-like behavior, MacFabe et al. investigated the effects of propionic acid (PPA), a short chain fatty acid and an important intermediate of cellular metabolism, on behavior, electrographic activity, neuropathology, and oxidative stress in rats exposed to intraventricular PPA [23].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com