Sentence examples for important integrator of from inspiring English sources

Finally, accumulation of damaged DNA in Cry2−/− cells suggests that Cry2 is a particularly important integrator of circadian rhythms and genomic integrity.

Abscisic acid acts as an important integrator of abiotic stress responses.

Adenosine monophosphate-activated kinase (AMPK) is an important integrator of signals that control cellular energy balance through the regulation of multiple biochemical pathways (Hardie et al. 1999).

The presence of NOS was described in several brain structures, including the circumventricular system, paraventricular (an important integrator of cardiovascular function regulations), and the supraoptic nuclei, all structures related to central angiotensinergic responses [ 12, 13].

In Arabidopsis, gibberellic acid (GA) activates the expression of AtSOC1 SUPPRESSOR OF OVER EXPRESSION OF CO 1) [ 32], an important integrator of several flowering pathways (discussed below), which in turn promotes flowering through its action on floral meristem identity genes or their products (Komeda 2004).

Nonetheless, our results suggest that these adaptor proteins are important integrators of signals leading to the neoplastic transformation and E-cadherin dysfunction in CRC harboring the deregulated Met receptor, and most likely other RTKs.

Other members in these three clusters include important integrators of signal transduction, such as LYN, PIK3C2A, SHP-2, SHIP-2, ERK1 (extracellular-signal-regulated kinase 1) and PLCL2 (summarized in Figure 4).

A further development of this idea has been put forward, whereby scaffolds such as dystroglycan are important integrators of ERK signalling, in that they direct ERK signalling to or away from the nucleus by acting as dimerisation sites for ERK activation [ 62] reviewed in [ 63].

On this view, the brain, like the heart and lungs, is a very important component of the interaction among body systems, but is not the supremely important integrator as suggested by the (mainstream) whole-brain approach.

The RIP kinases: crucial integrators of cellular stress.

Transcription factors are also important downstream integrators of signaling pathways and control gene expression to generate responses to nutrient limitation [ 34].