Sentence examples for important in activating from inspiring English sources

Plasmin is known to be very important in activating latent MMPs to active MMPs [ 40].

It has been shown that signal transducer and activator of transcription 1 (STAT1) is particularly important in activating IFN-γ and its antitumor effects.

Microbial glucuronidase activity also has been shown to be important in activating foodborne procarcinogens in the gut (Humblot et al. 2007), further illustrating the role of this enzyme in chemical metabolism.

Thus, a direct transcriptional activation of Snail by ATF3 may also be important in activating and/or maintaining Wnt/β-catenin signaling in these tumors through a positive feedback loop.

In parallel, these TRAFs are important in activating transcription factors NF-kB and/or IRF-3 by hMPV.

The models presented in Supplementary Figs 3 and 4 show ML scars to be important in activating tectonics, while the reduction in crust and mantle strength may also determine the dominant factor in tectonic evolution.

IFN- γ, besides having an important role in activating innate and adaptive immune responses, plays important roles in inhibiting cell proliferation and inducing apoptosis.

The nuclear import of mTOR has an important role in activating its cytoplasmic signalling (Bachmann et al, 2006).

In other settings, this property is shared by the canonical NF-κB activity which also plays an important role in activating both intrinsic genetic programs in cancer cells and the production of pro-oncogenic growth factors in cancer-associated stromal or inflammatory cells [3].

Since CRC is specifically expressed during the reproductive stage17, CRM4 might have an important role in activating YUC4 expression.

The in situ-synthesized Cu nanoparticles, amorphous state and carbon coating might play an important role in activating and enhancing the reversibility of the conversion reaction of CuxGeOy.