Sentence examples for important functional classes from inspiring English sources

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The observed median AUC is 56% averaged across all species and functional classes, and is higher for some important functional classes such as intermediary metabolism, DNA metabolism, and transport and binding proteins.

The larger comparative data set, used to define important functional classes for viruses, includes protein sequences from completely sequenced plasmids (all available at NCBI) and a phylogenetically balanced selection of cellular organisms from all of life, resulting in a total of 740,842 sequences.

The set of median-ranked genes has good coverage of all important functional classes compared to the top and bottom-ranked genes, so using their concatenation for phylogenetic inference potentially avoids systematic biases that can be caused by having a concentration of genes in the ranked list for some particular functional class.

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In the enriched functions of slow-evolving genes, we found a number of important house-keeping functional classes, including transcription, mRNA processing/splicing, translation, protein modification, metabolism, protein traffic, cell cycle, development and endocytosis (Table 1).

There are important differences among the different functional classes of pigmentation genes (table 2).

Adaptation of these energy metabolism related functional classes is important for parasites.

These results represent a major advance in characterizing spider genes, but due to the lack of comparisons with other tissues, it is unclear which genes or functional classes are important for silk synthesis [ 42].

More precisely, we defined functional classes as important for viruses using a larger comparative data set including cellular organisms from all branches of life for a total of 740,842 sequences (supplementary table S1, Supplementary Material online).

The classification of genes into gene families by Human Gene Nomenclature Committee (HGNC) on the basis of sequence similarity of the encoded proteins [ 4] and the availability of human genome sequence [ 5] allow us to carry out a comprehensive survey of a class of important functional element, namely the (TG/CA)n repeats.

The assignment of proteins to functional classes is an important principle in the understanding of complex cellular processes.

The analysis of these specific functional classes revealed an important heterogeneity of stress-specific responses among their members.

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