Sentence examples for important fulcrum from inspiring English sources

Next, we investigated an important fulcrum in insulin signaling pathway, the serine/threonine kinase Akt2, as well as genes of its downstream effectors, namely GLUT4 and forkhead box O3 (FO3O3).

Given the importance of NF-κB signalling in EC activation and promotion of the pro-inflammatory state (Kempe et al., 2005), we would suggest that caveolae regulation of NF-κB is an important fulcrum for control of inflammation.

The pooch gets some good laughs, but she's also an important narrative fulcrum, playing a key part in the film's biggest twist.

ABYEI, Sudan Thisis market town serves as kind of a fulcrum balancing perhaps the most important peace treaty in Africa.

British scholar Smart and Davies (1982) proposed a Roof Beam Tilt Theory, and its basic idea was to restrict the roof subsidence in entry from the coal side to the edge of gob side, he also put forward the standpoints that the inclination angle of roof and the rotation fulcrum position should act as two important parameters as to support design for retained entry.

From observations of residues important for the horizontal hydrophobic sliding of the fulcrum against the 30's strand in PRWT-SQV, Leu33′ makes two vdw interactions with both Ile13′ (4.2 Å, 3.8 Å) and Ile15′ (4.4 Å) facilitating the 30's strand to slide over the 'teens strand.

Work was important to Mr. Jalbert, but his family was his fulcrum.

In monomer A of PRWT-SQV, similar interactions important for the hydrophobic sliding of the cantilever and fulcrum are observed (Supporting Information Figure S3A).

In other words, PRG48T/L89M-SQV has lost important vdw interactions that facilitate the horizontal hydrophobic sliding of the fulcrum and 30's strand and has acquired many new vdw forces linking the 'teens strand of the fulcrum to the cantilever.

This presents an important and challenging public health question because PM standards are the fulcrum on which society decides how many people will be at increased health risk to ambient PM.

While Angola is a long way from wielding the broad influence of South Africa or Nigeria, it has fashioned itself into a regional power, and its military, as the fulcrum of power in the country, will remain for now an important engine of the country's aspirations -- and a crucial component in the fight against AIDS.