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NAP1L3 is important for proliferation and survival of human haematopoietic stem cells in vitro.
The breast tumor kinase (Brk), a mediator of cancer cell phenotypes important for proliferation, survival, and migration, was proposed as a potential target.
MiRNAs are also important for proliferation and cell-cycle regulation in human ESCs.
As ETS transcription factors are important for proliferation, survival and differentiation, we hypothesized that this could also be an important mechanism in VPC (for review see [15]).
Signaling by the transforming growth factor-β (TGF-β) superfamily of ligands is important for proliferation, differentiation, and cell fate determination during embryonic development and tissue homeostasis in the adult.
These results demonstrated that autophagy in basal cells is important for proliferation when starved, and suggests the recycling of basal cell components including nuclei as nutrients to support tip growth.
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Members of this family play important roles for proliferation, differentiation and apoptosis in a variety of cell types [3] [5].
Myb is an important TF for proliferation and differentiation of the intestinal epithelium.
The interference of Id proteins with the key regulatory bHLH proteins is therefore an important interaction for proliferation and differentiation.
This finding suggests that, while sterol might be important for Spiroplasma proliferation, it is not sufficient to induce proliferation under conditions of nutrient limitation.
These results implicate reduced proliferation rate of CYLD expressing MEF cells mediated by p38 and SRF activation, important for balancing proliferation and homoestasis of MEF cells.
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