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The fourth conserved region (C4) in the HIV-1 envelope glycoprotein (Env) gp120 is a structural element that is important for its function, as it binds to both the receptor CD4 and the co-receptor CCR5/CXCR4.
Interestingly, meikin also contains an STP motif that might bind PLK's PBD but whether this is important for its function is unclear as it is not well conserved.
The similar patterns of findings in AIV-lesioned birds and Area X-lesioned birds is consistent with the possibility that the AIV, or some components of it, may interact with the AFP, perhaps by transmitting to it a signal important for its function.
It is postulated that dimerization of ERV1 may be important for its function in physiology [ 29, 30].
Bone's elasticity is also important for its function giving the ability to the skeleton to withstand impact.
The post-translational modifications of a protein are highly important for its function (Guerra et al. 2015).
Interestingly, this region of A20 was previously shown to be important for its function in DNA replication.
It was demonstrated that the number of TCR molecules on a T cell is important for its function.
In assembling this nanoprobe, we have found that both the distance between substrates and the quantum dot surface, and the density of substrates are important for its function.
These findings suggest that N and C domains of Arl13b cooperatively regulate its ciliary localization and that N domain-dependent self-association of Arl13b may be important for its function in cilia biogenesis.
"Progesterone tends to slow down contractions of smooth muscle, the type of muscle that lines the GI tract that's important for its function and squeezing action," he explains.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com